body{
    margin:0.1em;
}
h2{
    padding-left:1.2em;
    font-size: 0.75em;
    margin-bottom: 0em;
}
h5{
    padding-left:4em;
    font-size: 0.5em;
    margin-top: 1em;
}
html{
    font-size: 2vw;
}

@media only screen and (min-width: 760px){
    .header {
        font-weight: bold;
        color: aquamarine;
        display: flex;
        font-size: 1.8em;
        background-color: rgb(23 75 105);
        padding: 0.5em;
    }
/*search box*/
    .search-box {
        position: absolute;
        right: 8.5em;
        top: 5.5em;
        /*background: #333;*/
        height: 0.5em;
        border-radius: 4em;
        padding: 0.15em;
        display: flex;
        justify-content: space-between;
        border: 0.1em solid rgb(23 75 105);
        border-width: 0.06em;
        width: 10em;
    }
    .search-cat {
        color: #eee;
        min-width: fit-content;
        height: 0.42em;
        border-radius: 4em;
        background: rgba(0, 0, 0, 0.15);
        display: flex;
        justify-content: center;
        align-items: center;
        color: #fff;
        cursor: pointer;
        text-decoration: none;
        margin: 0.001em;
        padding: 0em 0.11em 0em 0.11em;
        border: 0.05em solid rgb(23 75 105);
    }
.search-cat-sel:after{
    content:'>';
    font: 17px "Consolas", monospace;
    font-weight: bold;
    color: rgb(255, 255, 255);
  -webkit-transform: rotate(90deg);
  -moz-transform: rotate(90deg);
  -ms-transform: rotate(90deg);
  transform: rotate(90deg);
  padding-left: 2px;
  position: relative;
  pointer-events: none;
}
.search-cat-sel {
    color:#eee;
    min-width: fit-content;
    height: 1.5em;
    border-radius:4em;
    background: transparent;
    display: flex;
    justify-content: center;
    align-items: center;
    color: #000;
    cursor: pointer;
    text-decoration: none;
    outline: none;
    border:none;
    font-size: 0.3em;
    font-weight: bold;
}
.search-cat select {
    -webkit-appearance: none;
    -moz-appearance: none;
    appearance: none;
    
}
 
h6{
    margin-right: 5px;
    font-size: 0.5em;
    color: #777;
}
    .search-drop {
        width: 0.35em;
        height: 0.35em;
        border-radius: 1em;
        /*background: rgba(0, 0, 0, 0.29);*/
        display: flex;
        justify-content: center;
        align-items: center;
        color: #fff;
        cursor: pointer;
        text-decoration: none;
        /*z-index: 99;*/
    }
.search-drop i{
border: solid black;
border-width: 0 0.07em 0.07em 0;
display: inline-block;
padding: 0.04em;
margin-right: -0.01em;
/*z-index: 99;*/
}
.down{
    display: inline-block;
    transform: rotate(45deg);
    -webkit-transform: rotate(45deg);
    margin-right:1em;
}
    .search-btn {
        color: #eee;
        width: 0.55em;
        height: 0.55em;
        border-radius: 2em;
        background: rgba(0, 0, 0, 0.20);
        display: grid;
        justify-content: center;
        align-items: center;
        /*color: #fff;*/
        cursor: pointer;
        text-decoration: none;
        border: 0.05em solid rgb(23 75 105);
        margin: -0.06em -0.04em;
    }
    .search-txt {
        border: none;
        background: none;
        outline: none;
        padding: 0px 0px 0px 3px;
        color: #000;
        font-size: 0.35em;
        line-height: 1em;
        font-weight: bold;
        position: relative;
        top: -1.8em;
    }
.search-btn > i {
    font-size: 2em;
}
.search-box:hover > .search-btn {
    background: #fff;
    color: #000;
}
    .search-box:hover > .search-cat {
        background: #fff;
        color: #000;
    }
.search-box:hover > .search-cat > .search-drop {
    background: #fff;
    color: #000;
}
.search-box > .search-txt{
    width: 16em;
    
}
/* advance search*/
.advsearch-box{
        position:absolute;
        right:3em;
        top: 5.4em;
        /*background: #333;*/
        height: 1em;
        /* border-radius: 1em; */
        padding:0.4em;
        display: grid;
        justify-content: space-between;
        /* border-width: 5px; */
        /* border: solid black; */
        /* border-width: 2px; */
        width: 9.5em;
        font-size: 0.4em;
        align-content: center;
        margin-bottom: 0.5em;
        margin-top: 0.5em;
        text-decoration: none;
        color: #000;
}
/*menu*/
/*.nav{
    padding: 5px 0px 5px 12px;
    background-color: #333;
    display: grid;
}
.nav li {
    text-decoration: none;
    color: #fff;
}
.nav a:hover{
    background-color: #777;
    color: black;
}*/
    .menu {
        display: flex !important;
        list-style-type: none;
        text-decoration: none;
        padding: 0.1em 0em 0.3em 0.5em;
        background-color: rgba(0, 0, 0, 0.24)
    }
.menu li a{
    text-decoration: none;
    color: #000;
    padding: 0.04em 0.4em 0.04em 0.4em;
    
}    
ul {
    list-style-type: none;
    text-decoration: none;
    display: table-row;
}

/* first dropdown*/
.dropdown_comp{
    position: relative;
    display: inline-block !important;
}
.dropdown-content {
    display: none;
    position: absolute;
    background-color: #fff;
    width: 10em;
    box-shadow: 0em 0.1em 1em 0em rgba(0,0,0,0.2);
    z-index: 1;
}
.dropdown-content li a {
    color: #000;
    padding: 0.45em 0.9em;
    text-decoration: none;
    display: block;
}
.dropdown-content li a:hover{
    background-color: #777;
    color: #fff;
}
.menu a:hover{
    background-color: #777;
    color: #000;
}
.dropdown_comp:hover .dropdown-content{
    display: block;
}
/* second dropdown*/
.secdropdown{
    position: relative;
    display: inline-block;
}
.secdropdown-content {
    display: none;
    position: absolute;
    width: 15.5em;
    box-shadow: 0.1em 0.2em 0.2em 0.1px rgba(0,0,0,0.2);
    z-index: 1;
    left:100%;
    top:0%;
}
.secdropdown .secdropdown .secdropdown .secdropdown-content {
    display: none;
    position: absolute;
    background-color: #fff;
    width: 15em;
    box-shadow: 0em 0.1em 0.1em 0em rgba(0,0,0,0.2);
    z-index: 1;
    left:100%;
    top:0%;
}
.secdropdown-content a {
    color: black;
    padding: 12px 16px;
    text-decoration: none;
    min-width: max-content;
    display: block;
}
.secdropdown-content a:hover {
    background-color: #777;
    color: #fff;
}
.secdropdown .secdropdown .secdropdown .secdropdown-content a:hover {
    background-color: #777;
    color: #fff;
    width: 13.2em;
}
.secdropdown .secdropdown .secdropdown .secdropdown .secdropdown-content a:hover {
    background-color: #777;
    color: #fff;
    width: 16em;
}
.prodrug{
    font-size: 0.7em;
}
.prodrug:hover .secdropdown-content{
    display: block;
    left: 100%;
    top: 0%;
}
.secdropdown .secdropdown .secdropdown .prodrug:hover .secdropdown-content{
    display: block;
    left: 100%;
    top: 0%;
}

.verticle{
    border-right: 0.16em solid #fff;;
    border-radius: 0.01em;
    margin-top:0.1em;
    margin-bottom:0.1em;
    font-size: 0.7em;
}
/* Create three equal columns that floats next to each other */
.column {
    float: left;
    width: 15.31%;
    padding: 0.1em;
    background-color: #fff;
    height: 10.9em;
}
.columndata {
    float: left;
    width: 49.85%;
    padding: 0.5em 0em 0.5em 2.5em;
    background-color: #fff;
    
}
.column a {
    float: none;
    color: black;
    padding: 3em;
    text-decoration: none;
    display: block;
    text-align: left;
}
.columndata a {
    float: none;
    color: #333;
    padding: 0.105em;
    text-decoration: none;
    display: block;
    text-align: left;
    font-size: 0.65em;
    font-weight: bold;
}
.row{
    height: 8em;
}
.rowdata{
    height: auto;
}
.column a:hover {
    background-color: #777;
    color: #000;
}
  
/* Clear floats after the columns */
.row:after{
    content: "";
    display: table;
    clear: both;
}
.rowdata:after{
    content: "";
    display: table;
    clear: both;
}
footer {
    font-size: 0.5em;
    font-weight: bold;
    padding: 0.2em;
    text-decoration: none;
    background-color: #777;
    text-align: center;
    position: fixed;
    width: 100%;
    bottom: 0;
    left:0;
}
.browse h3{
    background-color: rgb(179, 179, 179);
    padding: 0.5em 1em 0.5em 1.4em;
    margin: 0 auto;
    font-size: 1em; 
}
.browse h5{
    background-color: rgb(179, 179, 179);
    padding: 1em 1em 0em 3em;
    margin: 0 auto; 
}
.browse p{
    background-color: rgba(50, 183, 164, 0.12);
    margin: 0 auto;
    padding: 0.3em 1.8em;
    font-size: 0.7em;
}
.container {
    display: none;
    
}
/* main result page */
    hr {
        margin-top: 0.087em;
        height: 0.18em;
        background-color: rgb(50 117 183);
        border: none;
    }
.table1 {
    width:100%; 
    border-collapse: collapse;
    margin-top: 0.5em;
}
.table2 {
    width:100%; 
    border-collapse: collapse;
    margin-top: 0.5em;
}

.img{
    display:block;
    width: 60%;
    height: auto;
    margin-left: auto;
    margin-right: auto;
    padding: 1em 0 0 0;
}
.prodrug_result_page{
    font-size: 1em;
    font-weight: bold;
    padding-left: 1.5em;
}
/*properties for heading of download link (SDF, MOL, SMILE)*/
.heading_row1 {
    background-color: #777;
    
}
.heading_row {
    background-color: #777;
    display: inline-block;
    width: 100%;
}
.heading_row2 {
    background-color: rgba(0, 0, 0, 0.24);
    display: inline-block;
    width: 97.5%;
    text-decoration:none;
    color: rgb(46, 88, 112);
    font-size: 0.9em;
    padding-left: 1.5em;
    font-weight: bolder;
}
.heading_row3 {
    background-color: rgba(0, 119, 91, 0.15);;
    display: inline-block;
    width: 97.5%;
    text-decoration:none;
    color: rgb(46, 88, 112);
    font-size: 0.7em;
    padding-left: 3em;
    font-weight: bolder;
}
.download_link{
    color:#333;
    font-weight: bold;
    font-size: 0.4em;
    text-decoration: none;
}
.download_link1{
    display:block;
    color:#666;
    font-weight: bold;
    font-size: 14px;
    text-decoration: none;
}
/*properties for data under all headings when screen size is more than 768 px*/
.heading_row_data{
    font-size: 0.7em;
    padding-left:  2em;
    font-weight: bold;
    margin: 1em auto;
    color: #fff;
}
.heading_row_lit p{
    padding:  0 2em 0 4em;
    margin: 0.5em auto 1em auto;
    -moz-text-align-last: left; 
    text-align: left;
    
}
.heading_row_lit2 p{
    /* padding:  0 2em 0 4em; */
    margin: 0.5em auto 0em auto;
    -moz-text-align-last: left; 
    text-align: left;
    
}
/*properties for heading of PDID when scren size is less then 768px */
.prodrug_id{
    font-size: 0.65em;
    font-weight: bold;
    padding-left: 3em;
    text-decoration: none;
    color: #333;
    
}
.extracteddata{
    text-decoration: none; 
    color: #32b7a4; 
    margin-left:10px;
}
.home_container{
    margin: auto 2.5em;
}
.home_container h1{
    font-size: 1.2em;
}
.home_container p{
    font-size: 0.7em;
}
.home_container ul li{
    font-size: 0.7em;
}
.collapsible3 {
    background-color: rgba(0, 0, 0, 0.24);
    color: rgb(46, 88, 112);
    cursor: pointer;
    width: 100%;
    border: none;
    padding: 0em 0px 0.1em 1.5em;
    text-align: left;
    outline: none;
    font-size: 0.94em;
    font-weight: bolder;
    font-family: initial;
    margin-top: 0.75em;
    
  }
 
  .collapsible2 {
    background-color: #f1f1f1;
    color: rgb(0, 0, 0);
    width: 100%;
    border:none;
    padding: 0em 0px 0em 1.6em;
    text-align: left;
    outline: none;
    font-size: 0.85em;
    font-weight: bolder;
    font-family: 'Times New Roman', Times, serif;
    margin-top: 0em;
  }
  .collapsible_mob .content{
      display: none !important;
  }
  span{
      color: #000;
      font-size: 1em;
      display: inline-flex;
      position: absolute;
      right: 0em;
      text-align: right;
      font-weight: bolder;
      right: 2em;
}
.span{
    color: #000;
    float: left;
    font-size: 1em;
    display: flex;
    position: absolute;
    right: 18em;
    text-align: right;
}
  
  /*.active, .collapsible:hover {
    
  }*/
  
  .content {
    padding: 0px 5px;
    display: none;
    overflow: hidden;
    background-color: #f1f1f1;
  }
  .content2 {
    padding: 0px 0.5em;
    display: block;
    overflow: hidden;
    background-color: #f1f1f1;
  }
  .collapsible_mob {
    display: none;
    }

  .form {
    margin: 1em 60em 0em 1.5em;;
    padding-left:1em;
    width: 30em; 
    font-size:0.7em
}
.formhead{
    display:block; 
    padding: 1em 0em 0em 1.8em; 
    font-size: 1em;
}
.formsubhead{
    padding: 1em 0em 0em 5.7em; 
    display:block; 
    color:rgb(104, 59, 59); 
    font-size: 1em;
}

    form input {
        position: relative;
        /*background: rgb(137, 137, 138);*/
        height: 2em;
        padding: 0em 1em;
        border-radius: 4em;
        color: #000;
        font-weight: bold;
        font-size: 0.7em;
        justify-content: space-between;
        border: solid rgb(50 117 183);
        border-width: 0.2em;
        margin: 1.5em 0em 0em 0em;
    }
.submitform{
    margin-left: 2em;
}
.downlink2 {
    text-align: center;
    display:block;
    width: 100%;

}
.downlink2 td {
    /* border-left: 0.08em solid #777; */
    line-height: 0.02em;
    background-color: rgb(0, 0, 0, 0.1);
    padding-bottom: 0.2em;
}
.conversion {
    text-align: center;
    display:table;
    width: 100%;
}
.conversiondata {
    text-align: center;
    display:table;
    width: 50%;
}
.conversion td{
    
    line-height: 0.02em;
    background-color: rgb(0, 0, 0, 0.1);
    padding-bottom: 0.29em;
}
.conversiondata td{
    
    line-height: 0.02em;
    padding-bottom: 0.2em;
}
.comment{
    position:relative;
    width: 40em;
    height: 10em;
    border-radius: 1em;
    color: #000;
    padding:1em;
    font-size: 0.5em;
    font-weight: bolder;
    margin: 1.5em 60em 0em 2.5em;
}
.columnmob a{
    display: none !important;
}
#mobdropd{
    display: none !important;
}
.columnmobtrgt a{
    display: none;}
.aboutpd p{
    font-size: 0.7em;
}
.aboutpd ul li{
    font-size: 0.7em;
}
.aboutpd{
    margin: auto 2.5em;
}
.aboutpd h3{
    font-size: 1em;
}
.download_icon{
    width:1.2em; 
    height:1.2em; 
    display:inline-table; 
    position:relative; 
    top:0.2em; 
    left:0.2em;
}
.download_link3{
    color:#333;
    font-weight: bold;
    font-size: 0.4em;
    text-decoration: none;
}
.subdata{
    padding-left:6em
}
.prodrugtd{
   /* padding-left: 0.06em;
    padding-right: 0.8em; */
    font-size:1.3em;
}
.activedrugtd{
   
    border-left: 0.1em solid #777;
    font-size:1.3em;
}
.help{
    font-size: 0.7em;
}
.columnmobtrgt{
    float: left;
    height: 15px;
    display: block;
    width: 49%;
    font-weight: bold;
    
}
.columnmobtrgt a{
    float: none;
    text-decoration: none;
    color: rgb(46, 88, 112);
    text-align: center;
    display: block;
    font-size: 12px;
}
.columnmobtrgt table tr {
    float: none;
    text-decoration: none;
    color: rgb(46, 88, 112);
    text-align: center;
    display: block;
    font-size: 12px;
    height: 4em;
    position: relative;
}
.columnmobtrgtdnld{
    float: left;
    height: 1em;
    display: block;
    width: 49.5%;
    font-weight: bold;
}
.columnmobtrgtdnld a{
    float: none;
    text-decoration: none;
    color: rgb(46, 88, 112);
    
    display: inline-table;
    font-size: 0.5em;

}
.rowmobtrgt{
    display:none;
}

.rowmobtrgt2{
    width: 98%;
    display: inline-table;
    position: absolute;
    left:0px;
    padding-left: 21em;
    /*margin-top: 1em;*/
   /* margin-bottom: 0.1em;*/
}
.columnmobtrgt a :active{
    background-color: #777;
}

.columnmobtrgt a:focus{
    background:rgb(119, 119, 119, 0.2);
}
.search-btn-mob{
    display:none;
}
.contact{
    font-size: 0.55em;
}

.contactpic{
    float:left;
    padding:0px 12px;
    width: 30.3333%;
    padding: 20px;
    border: 15px #000;
    display: inline;
}
.textbox{
    padding: 10px;
    text-align: center;
}
/* .developers{
    border: solid 2px #777;
} */
.developers img{
    width:14%;
    height:auto;
    display:block;
    position:relative;
    margin: 0 auto 0 auto;
    border-radius: 50%;
    border-style: solid;
    border-color: rgb(23, 75, 105);
    padding: 0.2em;
    border-width: 0.2em;
    box-shadow: 0 0px 55px 0 rgb(23, 75, 105, 0.95);
}
#grad{
    height: 640px;
    background-image: linear-gradient(to top, rgb(102 102 102 / 2%), rgb(50, 183, 164));
}
.arrange{
    content:"";
    display: table;
    clear: both;

}

.contactpic{
    float:left;
    padding:0px 12px;
    width: 30.33%;
    padding: 1.47vw;
    border: 15px #000;
    display: inline;
}
.textbox{
    padding: 10px;
    text-align: center;
}
/* .developers{
    border: solid 2px #777;
} */

.contbox{
    width:100%;
    margin: 0;
}
#grad{
    height: 25em;
    background-image: linear-gradient(to top, rgb(102 102 102 / 2%), rgb(50, 183, 164));
}
.arrange{
    content:"";
    display: table;
    clear: both;
}
.contact-table{
    width: 25%;
    font-size: 1.5em;
    border-color: rgb(23 75 105);
    border-style: solid;
    border-width:0.14em;
    border-radius: 4em;
    display:block;
    margin: 1.5em auto 1.5em auto;
    padding: 0.2em 0 0.2em 0;
}
#contct > div{
    width:calc(100%/2);
    
}
.strdwnld {
    display: grid; 
    margin-bottom:1.5em;
}

.cluster {
    display: block;
    border-radius: 30px;
    border: 2px solid purple;
    background: blue;
    backdrop-filter: blur(8px);
    width: 30px;
    height: 30px;
    
}
.tooltip {
    position: absolute;
  top: -30px;
  left: 50%;
  transform: translateX(-50%);
  background-color: #000;
  color: #fff;
  padding: 6px 10px;
  border-radius: 5px;
  opacity: 0;
  visibility: hidden;
  font-size: 14px;
  transition: all 0.3s ease;
}
.cluster:hover .tooltip {
  opacity: 1;
  visibility: visible;
  top: -50px;
}
.abtpdndimg{
    display:flex;
    width: 80%;
    position: relative;
    margin: 1em 10% 1em 10%;
}
.imgabtpdnd{
    width: 80%;
    height: auto;
    border-radius: 20%;
    border-style: solid;
    border-color: rgb(23 75 105);
    margin: 0.8em 0 0.8em 0;
    transition: transform 500ms ease-in-out;
    transform-origin: center;
    padding: 0.1em;
    box-shadow: 0 4px 8px 0 rgb(23, 75, 105, 0.35), 0 6px 20px 0 rgb(23, 75, 105, 0.55);
    margin-right: 0.3em;
}
 img.imgabtpdnd:hover{
     width: 100%;
    height: auto;
    border-radius: 20%;
    border-style: solid;
    border-color: rgb(23 75 105);
    transform: scale(1.7,1.7);
    transition: transform 500ms ease-in-out;
    cursor:pointer;
    display: inline-block;
    overflow: hidden;
    margin:0.5em 0 0.5em 0;
    
}
.similarity-button{
    border-radius:50%;
    font-size:0.5em;
    font-weight:bold;
    border-width:0.2em;
    box-shadow: 0 4px 8px 0 rgb(23, 75, 105, 0.35), 0 6px 20px 0 rgb(23, 75, 105, 0.55);
    border-color: #009eff;
    height:2.8em;
    width:2.8em;
    margin:0.5em;
    
}

}
@media only screen and (max-width: 760px){
    header{
        font-weight: bold;
        color:#fff;
        display: flex;
        font-size: 2.5em;
        background-color: #666;
    }
    header a {
        padding: 0.5em ;
    }
    
    .menu{
        display:none;
        list-style-type: none;
        text-decoration: none;
        padding: 1em 0.6em 1em 1em;
        background-color: #333;
    }
    .menu li {
        text-decoration: none;
        color: #fff;
        width: 100%; 
        padding: 7px 6px 7px 0px;
    }
    .verticle{
        border-right: 0px solid #fff;;
        padding: 2px;
        border-radius: 0.1em;
        margin-top: 0.3em;
        margin-bottom: 0.3em;
        font-size: 1.6em;
    }
    .menu li a:hover{
        background-color: #777;
        color: #000;
        width: 100%;
        
    }
    
    .bar{
        width: 0.9em;
        height: 0.09em;
        background-color: #fff;
        margin: 0.1em auto;
        border-radius: 0.5em;
        opacity: 1;
        left: 0;
        display: block;
    }
    
    .container {
        display: inline-grid;
        cursor: pointer;
        background-color: rgb(51, 51, 51, 0.8) ;
        height: 1.5em;
        width: 1.5em;
        align-content: center;
        margin: 0em 0.5em auto auto;
        
    }
    .container_box {
        display: inline-grid;
        background-color: #666 ;
        height: 1.5em;
        width: 1.5em;
        align-content: center;
        margin: 0.4em 0.5em auto auto;
        border-left: 0.1em solid black;
        padding-left: 0.5em;
    }
    .search-box2{
        position:relative;
        right: auto;
        left: 11em;
        background: #333;
        height: 3em;
        border-radius: 4em;
        padding:0.8em;
        display: grid;
        justify-content: space-between;
        border: solid black;
        border-width: 0.06em;
        width: 35em;
    }
    .search-box{
        display: none;
    }
    .advsearch-box{
        display: none;
    }
    .search-cat2 {
        color:#eee;
        width: 12em;
        height: 0.55;
        border-radius:4em;
        background: #000;
        display: flex;
        justify-content: center;
        align-items: center;
        color: #fff;
        cursor: pointer;
        text-decoration: none;
        margin:0.1em;
        padding: 0em;
        font-size: 1em;
    }
    .search-cat-sel2:after{
        content:'>';
        font: 17px "Consolas", monospace;
        font-weight: bold;
        color: rgb(255, 255, 255);
      -webkit-transform: rotate(90deg);
      -moz-transform: rotate(90deg);
      -ms-transform: rotate(90deg);
      transform: rotate(90deg);
      padding-left: 2px;
      position: relative;
      pointer-events: none;
    }
    .search-cat-sel2 {
        color:#eee;
        width: 6.5em;
        height: 1.5em;
        border-radius:4em;
        background: transparent;
        display: flex;
        justify-content: center;
        align-items: center;
        color: #777;
        cursor: pointer;
        text-decoration: none;
        outline: none;
        border:none;
        font-size: 1.4em;
        font-weight: bold;
    }
    .search-cat2 select {
        -webkit-appearance: none;
        -moz-appearance: none;
        appearance: none;
        
    }
    .search-drop2 {
        width: 1.35em;
        height: 1.35em;
        border-radius:1em;
        background: #777;
        display: flex;
        justify-content: center;
        align-items: center;
        color: #fff;
        cursor: pointer;
        text-decoration: none;
        z-index: 99;
        
    }
    .search-drop2 i{
    border: solid black;
    border-width: 0 0.35em 0.35em 0;
    display: inline-block;
    padding: 0.19em;
    margin-right:  0.01em;
    z-index: 99;
    }
    .down2{
        display: inline-block;
        transform: rotate(45deg);
        -webkit-transform: rotate(45deg);
        margin-right:1em;
    }
    .search-btn2 {
        color:#eee;
        width: 2.85em;
        height: 2.85em;
        border-radius:2em;
        background: #000;
        display: grid;
        justify-content: center;
        align-items: center;
        color: #fff;
        cursor: pointer;
        text-decoration: none;
        border: 0.02em solid #333;
        margin: 0.78em 32.65em;
        position: absolute;
    }
    .search-txt2 {
        border: none;
        background: none;
        outline: none;
        padding: 0;
        color: #fff;
        font-size: 1.6em;
        line-height: 1em;
        font-weight: bold;
        position: absolute;
        top: -1em;
        margin-left: 9em;
    }
    .search-btn2 > i {
        font-size: 2em;
    }
    .search-box2:hover > .search-btn2 {
        background: #fff;
        color: #000;
    }
    .search-box2:hover > .search-cat2 {
        background: #fff;
        color: #000;
    }
    .search-box2:hover > .search-cat2 > .search-drop2 {
        background: #fff;
        color: #000;
    }
    .search-box2 > .search-txt2{
        width: 10em;
        
    }
    .form {
        margin: 0em 60em 0em 1.5em;;
        padding:0.8em;
    }
    form input2{
            position: relative;
            background: rgb(137, 137, 138);
            height: 2.5em;
            padding-left: 1em;
            border-radius: 4em;
            color:#000;
            font-weight: bold;
            justify-content: space-between;
            border: solid black;
            border-width: 0.2em;
            margin: 1.5em 0em 0em 0em;
    }
    /* advance search*/
    .advsearch-box2{
            position: absolute;;
            left:8em;
            top: 3.9em;
            /*background: #333;*/
            height: 1em;
            /* border-radius: 1em; */
            padding:0.4em;
            display: grid;
            justify-content: space-between;
            /* border-width: 5px; */
            /* border: solid black; */
            /* border-width: 2px; */
            width: 9em;
            font-size: 2.3em;
            align-content: center;
            margin-bottom: 0.5em;
            margin-top: 0.5em;
            text-decoration: 0.1em underline;
            color: #000;
    }
    footer {
        font-size: 1em;
        font-weight: bold;
        padding: 0.2em;
        text-decoration: none;
        background-color: #777;
        text-align: center;
        position: fixed;
        width: 100%;
        bottom: 0;
        left:0;
        margin-top: 1em;
    }
    .browse h3{
        background-color: rgb(179, 179, 179);
        padding: 5px 10px 10px 10px;
        margin: 0 auto; 
    }
    .browse h5{
        background-color: rgb(179, 179, 179);
        padding: 10px 10px 0px 10px;
        margin: 0 auto; 
    }
    .browse p{
        background-color: rgba(50, 183, 164, 0.12);
        margin: 0 auto;
        padding: 10px 10px;
    }
    .table1 {
        width:100%; 
        border-collapse: collapse;
        padding: 1em;
        
    }
    .table2 {
        width:100%; 
        border-collapse: collapse;
        padding: 0.4em;
    }
    .img{
        display:block;
        width: 90%;
        height: auto;
        margin-left: auto;
        margin-right: auto;
        padding: 0.5em 0 0 0;
    }
    .prodrug_result_page{
        font-size: 2.2em;
        font-weight: bold;
        padding-left: 0.8em;
    }
    /*properties for heading of download link (SDF, MOL, SMILE)*/
.heading_row1 {
    background-color: #777;
}
.heading_row {
    background-color: #777;
}
.download_link{
    color:#333;
    font-weight: bold;
    font-size: 1em;
    text-decoration: none;
}
.download_link3{
    color:#333;
    font-weight: bold;
    font-size: 1.04em;
    text-decoration: none;
    padding-right: 2em;
}

.prodrug_id{
    font-size: 1.3em;
    font-weight: bold;
    padding-left: 1.5em;
    text-decoration: none;
    color: #333;
}
.collapsible_mob {
    background-color: #333;
    color: #fff;
    cursor: pointer;
    width: 100%;
    border: none;
    padding: 0.4em 0px 0.4em 0.5em;
    text-align: left;
    outline: none;
    font-size: 1.67em;
    font-weight: normal;
    font-family: 'Times New Roman', Times;
    
    }
.content {
    padding: 0px 5px;
    display: block;
    overflow: hidden;
    background-color: #777;
  }
  span{
      color: #000;
      float: left;
      font-size: 15px;
      display: inline-flex;
      position: absolute;
      right: 25px;
      text-align: right;
      padding: 0.2em;
      font-weight: bolder;
}
/*.search-txt a:active{

}*/
  
  .active, .collapsible_mob:hover {
    background-color: #555;
    
  }

  .content:hover{
    background-color: #777;
    color:black
  }
  .extracteddata{
    text-decoration: none; 
    color: rgb(50, 183, 164); 
    margin-left:10px;
}
ul {
    list-style-type: none;
    text-decoration: none;
    display: table-row;
    padding-left: 1em;
}
.menu li a{
    text-decoration: none;
    color: #fff;
    padding: 0.5em 0.6em 0.5em 0.6em;
    font-size: 1.6em;
}
.secdropdown-content {
    display: none;
}
.dropdown_comp{
    display: none;
}
.content .verticle{
    display: none;
}
.columnmob{
    float: left;
    padding: 2px;
    height: 20px;
    display: contents;
    
}
.columnmob a{
    float: none;
    text-decoration: none;
    color: rgb(46, 88, 112);
    text-align: center;
    display: block;
    padding: 0.4em;
    font-size: 1.1em;
}
.rowmob{
    background-color: rgb(0, 0, 0, 0.07);
    width: 20px;
    display: table;
    position: fixed;
    right: 2px;
    margin-top: 5px;
}
.collapsible {
    background-color: #777;
    color: rgb(0, 0, 0);
    cursor: pointer;
    width: 100%;
    border: none;
    padding: 0.2em 2.5em 0.2em 1em;
    text-align: left;
    outline: none;
    font-size: 1.7em;
    font-weight: bolder;
    font-family: 'Times New Roman', Times, serif;
    margin-top: 0.2em;
    margin-bottom: 0.25em;
  }
  .collapsible3 {
    background-color: rgba(0, 0, 0, 0.24);
    color: rgb(46, 88, 112);
    cursor: pointer;
    width: 100%;
    border: none;
    padding: 0em 0px 0.1em 1.6em;
    text-align: left;
    outline: none;
    font-size: 1.5em;
    font-weight: bolder;
    font-family: initial;
    margin-top: 0.5em;
    margin-left: 0.2em;
    margin-bottom: 0.2em;
    display: block;
  }
  .content {
    padding: 0px 5px;
    display: none;
    overflow: hidden;
    background-color: #777;
  }
  #mobdropd2 {
    padding: 0px 0.5em;
    overflow: hidden;
    background-color: #fff;
    margin-bottom: 0.4em;
    margin-top: -0.3em;
  }
  h2 {
    padding:0px 1.5em;
    font-size: 8px;
    margin-bottom: 0px;
}
h5{
    padding-left:4.2em;
    font-size: 1em;
    /* margin: 0.5em auto 2em 0em; */
}
.browse h5{
    background-color: rgb(179, 179, 179);
    padding: 1em 2em 0em 2.8em;
    margin: 0em auto;
    font-size: 1em; 
}
.browse h3{
    background-color: rgb(179, 179, 179);
    padding: 0.5em 1em 1em 1.8em;
    margin: 0em auto;
    font-size: 1.5em; 
}
.browse p{
    background-color: rgba(50, 183, 164, 0.12);
    margin: 0 auto;
    padding: 1em 2em;
    font-size: 1.35em;
}
.columnmobtrgt{
    float: left;
    height: 1.3em;
    display: block;
    width: 49%;
    font-weight: bold;
    
}
.columnmobtrgt a{
    float: none;
    text-decoration: none;
    color: rgb(46, 88, 112);
    text-align: center;
    display: block;
    font-size: 1.2em;
    background-color: #00000017;
}
.columnmobtrgtdnld{
    float: left;
    height: 1em;
    display: block;
    width: 48.5%;
    font-weight: bold;
    padding-left: 0.5em;
    
}
.columnmobtrgtdnld a{
    float: none;
    text-decoration: none;
    color: rgb(46, 88, 112);
    text-align: center;
    display: inline-block;
    font-size: 0.8em;
}
.rowmobtrgt{
    
    width: 96%;
    display: inline-table;
    position: absolute;
    left:0px;
    padding:0.3em 1.3em;
    margin-top: -7px;
    margin-bottom: 10px;
}
.columnmobtrgt a :active{
    background-color: #777;
}

.columnmobtrgt a:focus{
    background:rgb(119, 119, 119, 0.2);
}
.contenthide{
    display:none;
}
.conversion {
    text-align: center;
    display:table;
    width: 100%;
}
.conversion td{
    
    line-height: 1em;
    background-color: rgb(0, 0, 0, 0.1);
    padding-bottom: 0.29em;
}
.prodrugtd{
    padding-left: 2em;
    padding-right: 2em; 
    font-size:1.3em;
}
.activedrugtd{
    border-left: 0.2em solid #777;
    font-size:1.3em;
}
.downlink2 {
    text-align: center;
    display:block;
    width: 100%;

}
.downlink2 td {
    border-left: 0.08em solid #777;
    line-height: 0.02em;
    background-color: rgb(0, 0, 0, 0.1);
    padding-bottom: 0.2em;
}
.download_icon{
    width:1.3em; 
    height:1.3em; 
    display:inline-table; 
    position:relative; 
    top:0.2em; 
    left:0.2em;
}
.heading_row_data{
    font-size: 1.5em;
    padding-left:  1em;
    font-weight: bold;
    margin: 1em auto;
}
hr{
    margin-top: 0.3em;
    height: 0.18em;
    background-color: rgb(50, 183, 164);
    border:none;
}   
.heading_row_lit p{
    padding:  0 1.5em 0 0.5em;
    margin: 0.2em auto 0.2em auto;
    -moz-text-align-last: left; 
    text-align: left;
    
}
.home_container{
    margin: auto 2.5em;
}
.home_container h1{
    font-size: 1.7em;
}
.home_container p{
    font-size: 1.2em;
}
.home_container ul li{
    font-size: 1.2em;
    padding-bottom: 1em;
}
.aboutpd p{
    font-size: 1.2em;
}
.aboutpd ul li{
    font-size: 1.2em;
    padding-bottom: 0.8em;
}
.aboutpd{
    margin: auto 2.5em;
}
.aboutpd h3{
    font-size: 1.5em;
}
.form {
    margin: 1em 60em 0em 1.5em;;
    padding:0em;
}
.formhead{
    display:block; 
    padding: 1em 0em 0em 1.8em; 
    font-size: 1em;
}
.formsubhead{
    padding: 1em 0em 0em 2.9em; 
    display:block; 
    color:rgb(104, 59, 59); 
    font-size: 1.8em;
}
.submitform{
    margin-left: 2em;
    width: auto;
    padding-right: 1em;
}
form input{
    position: relative;
    background: rgb(137, 137, 138);
    height: 2em;
    padding-left: 1em;
    border-radius: 4em;
    color:#000;
    font-weight: bold;
    justify-content: space-between;
    border: solid black;
    border-width: 0.2em;
    margin: 1.5em 0em 0em 0em;
    width: 22em;
    font-size: 1.5em;
}
.comment{
    position:relative;
    width: 30em;
    height: 8em;
    border-radius: 1em;
    color: #000;
    padding:1em;
    font-size: 1.2em;
    font-weight: bolder;
    margin: 1em 0em 0em 2em;
}
.columndata {
    float: left;
    width: 49.8%;
    padding: 0.5em 0em 0.5em 2.5em;
    background-color: #fff;
    
}
.columndata a {
    float: none;
    color: #333;
    padding: 0.105em;
    text-decoration: none;
    display: block;
    text-align: left;
    font-size: 1.2em;
    font-weight: bold;
}
.column a {
    float: none;
    color: black;
    padding: 3em;
    text-decoration: none;
    display: block;
    text-align: left;
}
.content2 {
    padding: 0px 0.5em;
    display: block;
    overflow: hidden;
    background-color: #f1f1f1;
  }
h4{
    font-size: 2em;
}
.search-btn-mob{
    color:#eee;
    width: 0.1em;
    height: 0.4em;
    border-radius:2em;
    display: grid;
    justify-content: center;
    align-items: center;
    color: #fff;
    cursor: pointer;
    text-decoration: none;
    border: 0.07em solid #333;
    margin: 0.39em 0em auto 4.5em;
    
}
.mobsearchopt{
    position: absolute;
    display: flex;
    right: 18em;
    top: 15em;
}
.heading_row2 {
    background-color: rgba(0, 0, 0, 0.24);
    display: inline-block;
    width: 97.5%;
    text-decoration:none;
    color: rgb(46, 88, 112);
    font-size: 1.5em;
    padding-left: 1.5em;
    margin-top: 0.4em;
    font-weight: bolder;
}
.heading_row3 {
    background-color: rgba(0, 119, 91, 0.15);;
    display: inline-block;
    width: 97.5%;
    text-decoration:none;
    color: rgb(46, 88, 112);
    font-size: 1.2em;
    padding-left: 3em;
    margin-top: 0.3em;
    font-weight: bolder;
}
.contact{
    font-size: 0.55em;
}
.contactimg{
    width:8em !important;
    height:auto !important;
}
.contact-table{
    width: 100%;
    font-size: 1em;

}
.contactpic{
    float:left;
    padding:0px 12px;
    width: 30.3333%;
    padding: 20px;
    border: 15px #000;
    display: inline;
}
.textbox{
    padding: 10px;
    text-align: center;
}
/* .developers{
    border: solid 2px #777;
} */
.developers img{
    width:100%;
    height:auto;
    padding-left: 25%;    
}
#grad{
    height: 640px;
    background-image: linear-gradient(to top, rgb(102 102 102 / 2%), rgb(50, 183, 164));
}
.arrange{
    content:"";
    display: table;
    clear: both;

}
.contact-table{
    width: 100%;
    font-size: 1em;

}
.contactpic{
    width: 30.33%;
    border: 15px #000;
    display: inline;
    box-align:left;
}
.textbox{
    padding: 10px;
    text-align: center;
}
div.dev img{
    width:200px;
    width:200px;
    height:auto;
    border-radius:50%;    
}
.contbox{
    width: 100%;
    margin: 0;
}
#grad{
    height: 25em;
    background-image: linear-gradient(to left, rgb(102 102 102 / 2%), rgb(50, 183, 164));
}
.arrange{
    content:"";
    clear: both;
}
.contact-table{
    width: 100%;
    font-size: 1em;
}
.strdwnld {
    display: grid; 
    margin-bottom:0.1em;
}
}