| Phytochemical Name : Estradiol |
| PCNDIDE0069 |
| Pubchem CID : 5757 |
| Molecular formula: C18H24O2 |
| Canonical SMILES : CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O |
Synonymes : estradiol|beta-Estradiol|17beta-Estradiol|50-28-2|Oestradiol|Dihydrofolliculin|Estrace|Vivelle|Ovocyclin|progynon|Dihydrotheelin|Dihydroxyestrin|Diogynets|Gynoestryl|Aquadiol|Climara|Diogyn|Gynergon|Vagifem|Dimenformon|Follicyclin|Oestroglandol|Aerodiol|Bardiol|Corpagen|Divigel|Estraderm|Estrovite|Femestral|Ginosedol|Lamdiol|Macrodiol|Oestergon|Ovasterol|Ovastevol|Perlatanol|Primofol|Profoliol|Syndiol|Altrad|Evorel|Dihydromenformon|Estraldine|Estroclim|Estrogel|Menorest|Nordicol|Ovahormon|Femogen|Systen|Zumenon|estradiol-17beta|cis-Estradiol|D-Oestradiol|D-Estradiol|Estraderm TTS|Progynon DH|Climaderm|Compudose|Dermestril|Ovocycline|Trocosone|Estring|Innofem|Oesclim|Alora|Encore|Dihydroxyoestrin|Progynon-DH|Estrasorb|Fempatch|Gynestrel|Gynodiol|Microdiol|Oestrogynal|Ovociclina|Ovocylin|Tradelia|Esclim|Macrol|Menest|Zerella|Estroclim 50|17beta-Oestradiol|Oestradiol R|SK-Estrogens|Estring vaginal ring|Elestrin|Estrifam|Extrasorb|Ginedisc|Estreva|Evamist|Femtran|Trial SAT|Theelin, dihydro-|GynPolar|Compudose 200|Compudose 365|Sandrena Gel|Sisare Gel|Estrofem 2|Estradot|Menostar|Oestrogel|Zesteem|Estrofem Forte|Climara Forte|Profoliol B|Estraderm TTS 50|Oestradiol Berco|Estraderm MX|17b-Oestradiol|VIVELLE-DOT|NSC-9895|Estrapak 50|Oestradiolum|17 beta-Estradiol|Estradiol-17-beta|Estradiolum|Estrodiolum|Gelestra|3,17-Epidihydroxyestratriene|Dihydroxyesterin|cis-Oestradiol|Estrogens, esterified|17.beta.-Estradiol|B-Estradiol|Epiestriol 50|17beta oestradiol|Estra-1,3,5(10)-triene-3,17beta-diol|Oestradiol-17beta|Estradiol Anhydrous|E(sub 2)|17-beta-estradiol|Estradiol-17 beta|Estradiolum [INN]|Estradiolo [DCIT]|Oestradiol-17-beta|Elestrim|Estradiolo|Femanest|Femestrol|Minivelle|Yuvvexy|Estradiol-3,17beta|17-beta-OH-estradiol|3,17-beta-Estradiol|3,17-beta-Oestradiol|3,17-Epidihydroxyoestratriene|D-3,17beta-Estradiol|Sandrena 1|17b-Estradiol|Estraderm (TN)|[3H]-estradiol|17|A-estradiol|17|A-Oestradiol|Estrogel (TN)|Climara (TN)|Divigel (TN)|Estrace (TN)|Estring (TN)|Innofem (TN)|Vagifem (TN)|Vivelle (TN)|C18H24O2|(17beta)-Estra-1,3,5(10)-triene-3,17-diol|17.beta.-Oestradiol|CCRIS 280|Destradiol|Zesteen|17-beta-OH-oestradiol|(8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol|CHEBI:16469|Estradiol [USAN:INN]|HSDB 3589|3,17.beta.-Estradiol|D-3,17beta-Oestradiol|Estrodiolum [INN-Latin]|D-3,17-beta-Estradiol|D-3,17-beta-Oestradiol|.beta.-Estradiol|EINECS 200-023-8|.beta.-Oestradiol|Estrasorb (TN)|[3H]]estradiol|NSC-20293|Estradiol 17-beta|17-beta-oestradiol|component of Menrium|UNII-4TI98Z838E|IMVEXXY|TX-004HR|3,17beta-Estradiol|Estradiol, .beta.-|Estradiol-17.beta.|Estra-1,3,5(10)-triene-3,17-diol (17beta)-|Oestradiol-17.beta.|Estraderm TTS 100|17-.beta.-oestradiol|4TI98Z838E|ESTRADIOL HEMIHYDRATE|Oestra-1,3,5(10)-triene-3,17beta-diol|17.beta.-OH-estradiol|17-.BETA.-Estradiol|17.beta.-OH-oestradiol|17beta estradiol (E2)|17beta-Estra-1,3,5(10)-triene-3,17-diol|WC3011|1,3,5-Estratriene-3,17-beta-diol|CHEMBL135|(17beta)-estra-1(10),2,4-triene-3,17-diol|D-3,17.beta.-Estradiol|WC-3011|D-3,17.beta.-Oestradiol|Estradiol [USP:INN:BAN]|3,17beta-Dihydroxyestra-1,3,5-triene|Estra-1,3,5(10)-triene-3,17-diol, (17beta)-|3,17beta-Dihydroxyoestra-1,3,5-triene|3,17-beta-Dihydroxyoestra-1,3,5-triene|MLS000069494|3,17b-Dihydroxyestra-1,3,5(10)-triene|(+)-3,17.beta.-Estradiol|141290-02-0|DTXSID0020573|Estra-1,3,5(10)-triene-3,17-beta-diol|Estradiol valerate metabolite e2|BIJUVA COMPONENT ESTRADIOL|Oestra-1,3,5(10)-triene-3,17-beta-diol|3,17-beta-Dihydroxyestra-1,3,5(10)-triene|NSC9895|3,17-beta-Dihydroxy-1,3,5(10)-oestratriene|ANGELIQ COMPONENT ESTRADIOL|EC 200-023-8|ORIAHNN COMPONENT ESTRADIOL|PREFEST COMPONENT ESTRADIOL|17-beta-Estra-1,3,5(10)-triene-3,17-diol|17beta-Oestra-1,3,5(10)-triene-3,17-diol|17-beta-Oestra-1,3,5(10)-triene-3,17-diol|ACTIVELLA COMPONENT ESTRADIOL|ESTRADIOL COMPONENT OF BIJUVA|COMBIPATCH COMPONENT ESTRADIOL|[3H]E2|CMC_11154|ESTRADIOL COMPONENT OF ANGELIQ|ESTRADIOL COMPONENT OF ORIAHNN|ESTRADIOL COMPONENT OF PREFEST|CLIMARA PRO COMPONENT ESTRADIOL|Estra-1,3,5(10)-triene-3,17-diol (17.beta.)-|(8R,9S,13S,14S,17S)-13-Methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol|E2|ESTRADIOL COMPONENT OF ACTIVELLA|SL-1100|ESTRADIOL COMPONENT OF COMBIPATCH|NCGC00091544-04|ESTRADIOL COMPONENT OF CLIMARA PRO|SMR000059126|E0025|3,17beta-Dihydroxyestra-1,3,5(10)-triene|E 8875|3,17.beta.-Dihydroxyestra-1,3,5(10)-triene|Methyl 1-cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate.|Benzogynestry|Estropause|S-21400|Estasorb|(1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2(7),3,5-triene-5,14-diol|[2,4,6,7-3H]-E2|E 2|DTXCID80573|ESTRADIOL (USP MONOGRAPH)|ESTRADIOL [USP MONOGRAPH]|ESTRADIOL IMPURITY A (IP)|ESTRADIOL IMPURITY A [IP]|.alpha.-Estradiol|17?-Estradiol|Activella (Salt/Mix)|Combipatch (Salt/Mix)|Estradiol-17 alpha|Climara Pro (Salt/Mix)|3,17-.beta.-Oestradiol|ETHINYLESTRADIOL IMPURITY D (EP IMPURITY)|ETHINYLESTRADIOL IMPURITY D [EP IMPURITY]|3,3,5(10)-triene|SR-01000075866|oestrodiol|beta-Oestradiol|delta-Estradiol|dihydro-Theelin|estradiol-|NSC20293|beta -estradiol|alpha-Oestradiol|delta-Oestradiol|Estrogel HBF|1jgl|1lhu|1qkt|1qku|[3H]estradiol|1,3,5-Estratriene-3,17.beta.-diol|CAS-50-28-2|Activella (TN)|Estradiol 17B|Progynova (TN)|Elestrin (TN)|Estrofem (TN)|Menostar (TN)|.alpha.-Oestradiol|Estra-1,3,5(10)-triene-3,17-diol|Prestwick_207|3,17b-Estradiol|Angeliq (TN)|Bio-E-Gel|Fem7|[3H]-Estrogen|17 ?-Estradiol|3,17.beta.-Dihydroxyestra-1,3,5-triene|3,17.beta.-Dihydroxyoestra-1,3,5-triene|EvaMist (TN)|Therapeutic Estradiol|Vivelle-Dot (TN)|Alora (TN)|1,3,5,(10)-Estratrien-3,17.beta.-diol|Beta-estradiol (E2)|Estra-1,3,5(10)-triene-3,17.beta.-diol|Estraderm TTS (TN)|Oestra-1,3,5(10)-triene-3,17.beta.-diol|2j7x|3,17.beta.-Dihydroxy-1,3,5(10)-estratriene|3,17.beta.-Dihydroxy-1,3,5(10)-oestratriene|3,3,5-triene|[3H]17beta-estradiol|ESTRADIOL [INN]|ESTRADIOL [JAN]|Estradiol acetate (TN)|(17?)-Estra-1,3,5(10)-triene-3,17-diol|17.beta.-Estra-1,3,5(10)-triene-3,17-diol|ESTRADIOL [MI]|Estrasorb Topical (TN)|ESTRADIOL [HSDB]|ESTRADIOL [INCI]|Estradiol valerate (TN)|17.beta.-Oestra-1,3,5(10)-triene-3,17-diol|Opera_ID_1688|Prestwick0_000441|Prestwick1_000441|Prestwick2_000441|Prestwick3_000441|Spectrum5_002055|17beta-estradiol (E2)|ESTRADIOL [VANDF]|Estradiol cypionate (TN)|3,17beta-Dihydroxy-1,3,5(10)-estratriene|alpha-estradiol (obsolete)|beta-Estradiol, >=98%|bmse000642|D08QMX|Epitope ID:136018|(+)-3,17b-Estradiol|ESTRADIOL [USP-RS]|ESTRADIOL [WHO-DD]|SCHEMBL8049|(+)-3,17beta-Estradiol|Estradiol (JAN/USP/INN)|Tritiated estradiol-17-beta|BIDD:PXR0065|Lopac0_000503|BSPBio_000482|BSPBio_001065|KBioGR_000405|KBioGR_002269|KBioSS_000405|KBioSS_002270|MLS000758312|MLS001076331|MLS001424022|BIDD:ER0125|SPBio_002421|ESTRADIOL [GREEN BOOK]|BPBio1_000532|GTPL1012|GTPL1013|ESTRADIOL [ORANGE BOOK]|NIOSH/KG7030000|UNII-125DP6010H|BDBM17292|KBio2_000405|KBio2_002269|KBio2_002973|KBio2_004837|KBio2_005541|KBio2_007405|KBio3_000769|KBio3_000770|KBio3_002749|1a52|1g50|2d06|cMAP_000005|Bio1_000403|Bio1_000892|Bio1_001381|Bio2_000363|Bio2_000843|HMS1362E07|HMS1569I04|HMS1792E07|HMS1990E07|HMS2051C17|HMS2090E18|HMS2096I04|HMS2236H04|HMS3261F07|HMS3403E07|HMS3713I04|HMS3884A08|beta-Estradiol, analytical standard|(8S,9S,13S,14S,17S)-13-Methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol|BCP08579|ESTRADIOL 17-BETA [VANDF]|HY-B0141|Tox21_111148|Tox21_202057|Tox21_300288|Tox21_500503|1,5-Estratriene-3,17.beta.-diol|HB2494|LMST02010001|LS-137|s1709|Estradiol-17-beta-6,7-(sup 3)H|[2,4,6,7-3H]-17beta-estradiol|AKOS015896570|CCG-100808|CS-1938|CS-O-11584|DB00783|LP00503|NC00058|SDCCGSBI-0050487.P002|IDI1_002118|SMP1_000121|1,3,5(10)-estratriene-3,17b-diol|NCGC00091544-00|NCGC00091544-01|NCGC00091544-02|NCGC00091544-05|NCGC00091544-06|NCGC00091544-07|NCGC00091544-09|NCGC00091544-10|NCGC00091544-11|NCGC00091544-12|NCGC00091544-13|NCGC00091544-14|NCGC00091544-15|NCGC00091544-16|NCGC00091544-18|NCGC00091544-27|NCGC00179321-01|NCGC00179321-02|NCGC00254177-01|NCGC00259606-01|NCGC00261188-01|17-E|AC-22346|AS-13729|CPD000059126|Estra-1,3,5(10)-triene-3,17b-diol|Oestra-1,3,5(10)-triene-3,17b-diol|WLN: L E5 B666TTT&J E1 FQ OQ|Estra-1,5(10)-triene-3,17.beta.-diol|Estradiol, meets USP testing specifications|3,17beta-dihydroxyestra-1,3,5(10)-trien|Estra-1,3,5(10)-triene -3,17beta-diol|EU-0100503|KG70300000|Oestra-1,5(10)-triene-3,17.beta.-diol|3,17-dihydroxy-delta(1,3,5-10)-estratriene|C00951|D00105|EN300-119518|(17b)-Estra-1,3,5(10)-triene-3,17-diol|13b-Methyl-1,3,5(10)-gonatriene-3,17b-ol|17-decahydrocyclopenta[a]phenanthrene-3,17-diol|17.beta.-Estra-1,5(10)-triene-3,17-diol|17.beta.-Oestra-1,5(10)-triene-3,17-diol|17-beta-Estradiol 100 microg/mL in Acetonitrile|Q422416|SR-01000721892|13beta-Methyl-1,3,5(10)-gonatriene-3,17beta-ol|Estra-1,3,5(10)-triene-3,7-diol(17.beta.)-|Estra-1,3,5(10)-trieno-3,17-diol (17?)-|Estra-1,5(10)-triene-3,17-diol (17.beta.)-|ESTRADIOL BENZOATE IMPURITY A [EP IMPURITY]|ESTRADIOL VALERATE IMPURITY A [EP IMPURITY]|Q-201503|SR-01000075866-1|SR-01000075866-4|SR-01000721892-3|BRD-K18910433-001-04-4|BRD-K18910433-001-43-2|estra-1(10),2,4-triene-3,17-diol, (17beta)-|Estra-1,5(10)-triene-3,17-diol, (17.beta.)-|Estra-1,3,5(10)-triene-3,17-diol, (17.beta.)-|Z1521553843|B8B5AEF5-4957-49EB-A14F-444A8212C482|beta-Estradiol, BioReagent, powder, suitable for cell culture|Estradiol, United States Pharmacopeia (USP) Reference Standard|13.BETA.-METHYL-1,3,5(10)-GONATRIENE-3,17.BETA.-OL|beta-Estradiol, powder, gamma-irradiated, suitable for cell culture|Estra-1,3,5(10)-triene-3,17-diol, (6,7-(sup 3)H,17-beta)-|Estradiol, Pharmaceutical Secondary Standard; Certified Reference Material|(13S,17S)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-beta-diol|(1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0;{2,7}.0;{11,15}]heptadeca-2,4,6-triene-5,14-diol|(1S,10R,11S,14S,15S)-15-methyltetracycl |
| Structure | |
| 3D structure | 2D structure |
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| Log Po/w (iLOGP) : 2.590 |
| Log Po/w (XLOGP3) : 4.010 |
| Log Po/w (WLOGP) : 3.610 |
| Log Po/w (MLOGP) : 3.530 |
| Log Po/w (SILICOS-IT) : 3.250 |
| Consensus Log Po/w : 3.400 |

